ATE1 Antibody (YA2178)
(Synonyms: Arginyltransferase 1; R-transferase 1)ATE1 Antibody (YA2178) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATE1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Rat
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 |
Product Details
ATE1 Antibody (YA2178) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATE1.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Rat
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Observed Molecular WeightObserved band size: 59 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 59 kDa
Entrez Gene: 11101 Human ; 11907 Mouse ; 293526 Rat
SwissProt: O95260 Human ; Q9Z2A5 Mouse ;
OMIM: 607103 Human
A synthetic peptide of human ATE1
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ATE1 is involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. Does not arginylate cysteine residues[1].
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Subcellular Localization
Nucleus; Cytoplasm
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Isoforms & Post-Translational Modification
O95260 has 2 isomers: O95260-1: 59090 Da (predicted); O95260-2: 59032 Da (predicted).
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Subunit
Monomer. Interacts with LIAT1; LIAT1 is not a substrate of ATE1, the interaction takes place in the cytoplasm and seems to increase ATE1 arginyltransferase activity
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SwissProt ID
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Synonyms
Arginyltransferase 1; R-transferase 1
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Research Field
Neuroscience
Documentation
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