Bmi-1 Antibody (YA7611)
(Synonyms: PCGF4, RNF51, BMI1, Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51)Based on 1 Customer Validation
Bmi-1 Antibody (YA7611) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Bmi-1.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-P, ICC/IF, IP, ELISA
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA
-
Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
IP
IP: Immunoprecipitation
|
|---|---|---|---|---|---|
| Dilution Ratio | 1:100-1:500 | 1:2000-1:10000 | 1:200-1:1000 | 1:5000-1:20000 | 1:50-1:200 |
Product Details
Bmi-1 Antibody (YA7611) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Bmi-1.
-
Host Rabbit
-
Clonality Monoclonal,Recombinant
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 43 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 37 kDa
The exact sequence is proprietary to MCE.
Endogenous
Protein A affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA
-
Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
B cell-specific Moloney murine leukemia virus integration site 1 (BMI1), a component of the polycomb repressive complex 1 (PRC1), is recognized as a polycomb protein that prevents premature senescence and maintains the self-renewal capacity of stem cells.
-
Subcellular Localization
Nucleus,Cytoplasm
-
Expression
Induction: Down-regulated by oxidative stress
-
Isoforms & Post-Translational Modification
P35226: 326 amino acids, molecular weight 36949 Da.
-
Subunit
Component of a PRC1-like complex (PubMed:12167701, PubMed:15386022, PubMed:19636380, PubMed:21282530, PubMed:21772249, PubMed:25355358, PubMed:26151332)
-
SwissProt ID
-
Synonyms
PCGF4, RNF51, BMI1, Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51
Documentation