BTBD10 Antibody (YA8741)(PBS only)
(Synonyms: GMRP-1; GMRP1)BTBD10 Antibody (YA8741) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to BTBD10.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
BTBD10 Antibody (YA8741) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to BTBD10.
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Host Mouse
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 53.6 kDa
Full length human recombinant protein of human BTBD10 produced in E.coli.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
BTBD10 plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and accelerating the growth of pancreatic beta cells
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Subcellular Localization
Nucleus,Cytoplasm
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Expression
Tissue_Specificity: Ubiquitously expressed. Highly expressed in adult brain, testis, aorta and small intestine and weakly expressed in the heart, lung, liver, kidney, pancreas, spleen, thymus, prostate, ovary and colon. Down-regulated in glioma -
Isoforms & Post-Translational Modification
Q9BSF8 has two isomers: Q9BSF8-1: 53779 Da (predicted); Q9BSF8-2: 54406 Da (predicted).
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Subunit
Interacts (via C-terminal 330-amino-acid region) with AKT1; AKT2 and AKT3
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SwissProt ID
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Synonyms
GMRP-1; GMRP1
Documentation
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