Caspr1 Antibody (YA3371)
(Synonyms: Caspr; Caspr1; CNTNAP; Cntnap1; Contactin associated protein 1; MHDNIV; NCP1; Neurexin-4; Nrxn4; p190; Paranodin)Based on 1 Customer Validation
Caspr1 Antibody (YA3371) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspr1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-1:2000 | 1:50-1:100 |
Product Details
Caspr1 Antibody (YA3371) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspr1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 165 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 156 kDa
Entrez Gene: 8506 Human ; 53321 Mouse ; 84008 Rat
SwissProt: P78357 Human ; O54991 Mouse ; P97846 Rat
OMIM: 616286 Human
A synthesized peptide derived from human Caspr aa700-770/1384.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Envío
Shipping with blue ice.
Background
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Function
Caspr1 is required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells
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Subcellular Localization
Membrane; Single-pass type I membrane protein; Cell junction, paranodal septate junction
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Expression
Tissue_specificity:Predominantly expressed in brain. Weak expression detected in ovary, pancreas, colon, lung, heart, intestine and testis -
Subunit
Interacts with CNTN1/contactin in cis form
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SwissProt ID
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Synonyms
Caspr; Caspr1; CNTNAP; Cntnap1; Contactin associated protein 1; MHDNIV; NCP1; Neurexin-4; Nrxn4; p190; Paranodin
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Research Field
Neuroscience
Documentación