Caspr1 Antibody (YA3371)

(Synonyms: Caspr; Caspr1; CNTNAP; Cntnap1; Contactin associated protein 1; MHDNIV; NCP1; Neurexin-4; Nrxn4; p190; Paranodin)
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Based on 1 Customer Validation

Caspr1 Antibody (YA3371) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspr1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

  • Conjugation:
    Non-conjugated

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:1000-1:2000 1:50-1:100

Product Details

Descripciòn

Caspr1 Antibody (YA3371) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspr1.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 165 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 156 kDa
Species Reactivity Database
Immunogen

A synthesized peptide derived from human Caspr aa700-770/1384.

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Envío

    Shipping with blue ice.

Background

  • Function

    Caspr1 is required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells

  • Subcellular Localization

    Membrane; Single-pass type I membrane protein; Cell junction, paranodal septate junction

  • Expression


    Tissue_specificity:Predominantly expressed in brain. Weak expression detected in ovary, pancreas, colon, lung, heart, intestine and testis

  • Subunit

    Interacts with CNTN1/contactin in cis form

  • SwissProt ID

    P78357

  • Gene ID
  • Synonyms

    Caspr; Caspr1; CNTNAP; Cntnap1; Contactin associated protein 1; MHDNIV; NCP1; Neurexin-4; Nrxn4; p190; Paranodin

  • Research Field

    Neuroscience

Caspr1 Antibody (YA3371) Related Classifications

MOQ
Minimum order quantity
100 mg

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