Caspr2 Antibody (YA2970)
(Synonyms: AUTS15; CDFE; CNTNAP2; CNTP2; NRXN4; PTHSL1)Caspr2 Antibody (YA2970) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspr2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 |
Product Details
Caspr2 Antibody (YA2970) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Caspr2.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 160 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 148 kDa
A synthesized peptide derived from human CNTP2 aa1300-1331.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Caspr2 is required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction
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Subcellular Localization
Membrane; Single-pass type I membrane protein; Cell projection, axon; Cell junction, paranodal septate junction
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Expression
Tissue_specificity:Predominantly expressed in nervous system -
Isoforms & Post-Translational Modification
Q9UHC6 has 2 isomers: Q9UHC6-1: 148167 Da (predicted); Q9UHC6-2: 11899 Da (predicted).
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Subunit
Interacts (via C-terminus) with KCNA2 (PubMed:10624965). Interacts with GPR37 (PubMed:25977097)
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SwissProt ID
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Synonyms
AUTS15; CDFE; CNTNAP2; CNTP2; NRXN4; PTHSL1
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Research Field
Neuroscience
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