CCDC51 Antibody (YA7054)

Cat. No.: HY-P87371: Data Sheet User Guide for Antibodies
FAQs
Technical Support

CCDC51 Antibody (YA7054) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCDC51.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CCDC51 Antibody (YA7054) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCDC51.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 46 kDa;

Observed band size: 46 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q96ER9

Immunogen

Recombinant protein with Human CCDC51 aa 311-411 / / 411.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:200

Sensitivity	Endogenous	Purity	Protein A affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Pore-forming subunit of the mitochondrial ATP-gated potassium channel (mitoK(ATP)) (PubMed:31435016). Together with ATP-binding subunit ABCB8/MITOSUR of the mitoK(ATP) channel, mediates ATP-dependent K(+) currents across the mitochondrial inner membrane (PubMed:31435016). An increase in ATP intracellular levels closes the channel, inhibiting K(+) transport, whereas a decrease in ATP levels enhances K(+) uptake in the mitochondrial matrix. May contribute to the homeostatic control of cellular metabolism under stress conditions by regulating the mitochondrial matrix volume (PubMed:31435016)

Subcellular Localization：Mitochondrion inner membrane,Mitochondrion inner membrane

Expression：
Tissue_Specificity: Isoform 1: Widely expressed (PubMed:31435016). Isoform 2: Expression is barely detectable (PubMed:31435016)

Isoforms & Post-Translational Modification：Q96ER9 has two isomers: Q96ER9-1: 45811 Da (predicted); Q96ER9-2: 33657 Da (predicted).

Subunit：The mitochondrial potassium channel (mitoK(ATP)) is composed of 4 subunits of CCDC51/MITOK and 4 subunits of ABCB8/MITOSUR

Synonyms

5730568A12Rik antibody; AI551049 antibody; CCD51_HUMAN antibody; CCDC51 antibody; Coiled coil domain containing 51 antibody; Coiled-coil domain-containing protein 51 antibody; FLJ12436 antibody; RGD1311466 antibody

Documentation

User Guide for Antibodies (1077 KB)