CCDC51 Antibody (YA7054)
(Synonyms: 5730568A12Rik antibody; AI551049 antibody; CCD51_HUMAN antibody; CCDC51 antibody; Coiled coil domain containing 51 antibody; Coiled-coil domain-containing protein 51 antibody; FLJ12436 antibody; RGD1311466 antibody)CCDC51 Antibody (YA7054) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCDC51.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IHC-P
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Reactivity :
Human
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Formulation:
Supplied in 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:200 |
Product Details
CCDC51 Antibody (YA7054) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCDC51.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 46 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 46 kDa
Recombinant protein with Human CCDC51 aa 311-411 / / 411.
Endogenous
Protein A affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CCDC51 is a Pore-forming subunit of the mitochondrial ATP-gated potassium channel (mitoK(ATP)). Together with ATP-binding subunit ABCB8/MITOSUR of the mitoK(ATP) channel, mediates ATP-dependent K(+) currents across the mitochondrial inner membrane. An increase in ATP intracellular levels closes the channel, inhibiting K(+) transport, whereas a decrease in ATP levels enhances K(+) uptake in the mitochondrial matrix. May contribute to the homeostatic control of cellular metabolism under stress conditions by regulating the mitochondrial matrix volume[1].
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Subcellular Localization
Mitochondrion inner membrane,Mitochondrion inner membrane
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Expression
Tissue_Specificity: Isoform 1: Widely expressed (PubMed:31435016). Isoform 2: Expression is barely detectable (PubMed:31435016) -
Isoforms & Post-Translational Modification
Q96ER9 has two isomers: Q96ER9-1: 45811 Da (predicted); Q96ER9-2: 33657 Da (predicted).
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Subunit
The mitochondrial potassium channel (mitoK(ATP)) is composed of 4 subunits of CCDC51/MITOK and 4 subunits of ABCB8/MITOSUR
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SwissProt ID
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Synonyms
5730568A12Rik antibody; AI551049 antibody; CCD51_HUMAN antibody; CCDC51 antibody; Coiled coil domain containing 51 antibody; Coiled-coil domain-containing protein 51 antibody; FLJ12436 antibody; RGD1311466 antibody
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