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CCT4 Antibody (YA8805)(PBS only)

(Synonyms: CCT-DELTA; Cctd; SRB)

CCT4 Antibody (YA8805) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCT4.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • CCT4 Antibody (YA8805)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:150-500

Product Details

Description

CCT4 Antibody (YA8805) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCT4.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 57.7 kDa
Immunogen

Full length human recombiant protein of human CCT4 produced in E.coli.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CCT4 component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia[1][2][3][4][5].

  • Subcellular Localization

    Cytoplasm,Melanosome,Cytoplasm, cytoskeleton, microtubule organizing center, centrosome,Cytoplasm, cytoskeleton, cilium basal body

  • Isoforms & Post-Translational Modification

    P50991 has two isomers: P50991-1: 57924 Da (predicted); P50991-2: 54720 Da (predicted).

  • Subunit

    Component of the chaperonin-containing T-complex (TRiC), a hexadecamer composed of two identical back-to-back stacked rings enclosing a protein folding chamber (PubMed:20080638, PubMed:25467444, PubMed:36493755, PubMed:35449234, PubMed:37193829)

  • SwissProt ID

    P50991

  • Synonyms

    CCT-DELTA; Cctd; SRB

CCT4 Antibody (YA8805)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • CCT4 Antibody (YA8805)(PBS only) Product Image