CD34 Antibody (YA6360)
(Synonyms: CD34 antigen; CD34 molecule; Cluster designation 34; Hematopoietic progenitor cell antigen CD34; HPCA1; CD34_HUMAN.)CD34 Antibody (YA6360) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD34.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IHC-F, IF-Tissue, IP
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IP
IP: Immunoprecipitation
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|---|---|---|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:100-500 | 1:100-500 | 1:100-500 | 1:20-50 |
Product Details
CD34 Antibody (YA6360) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD34.
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Host Rabbit
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 39 kDa
KLH conjugated synthetic peptide derived from human CD34 aa 350-385
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD34 is a highly glycosylated type I transmembrane mucin-like glycoprotein and a surface marker of hematopoietic stem cells and hematopoietic progenitor cells. CD34 is mainly involved in stem cell adhesion, migration, self-renewal, and bone marrow homing, and participates in angiogenesis in vascular endothelial cells. CD34 is widely used in hematopoietic stem cell transplantation, immunophenotyping of acute leukemia, flow cytometry sorting, and tumor microvessel density detection.
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Subcellular Localization
Membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:It is selectively expressed on hematopoietic progenitor cells and small vascular endothelial cells in various tissues. -
Isoforms & Post-Translational Modification
CD34 has 2 isomers: P28906-1: 40716 Da (predicted); P28906-2: 35011 Da (predicted).
Highly glycosylated;Phosphorylated on serine residues by PKC -
SwissProt ID
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Synonyms
CD34 antigen; CD34 molecule; Cluster designation 34; Hematopoietic progenitor cell antigen CD34; HPCA1; CD34_HUMAN.
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