Cenexin1 Antibody
(Synonyms: CT134, ODF84, ODF2/1, ODF2/2)Cenexin1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Cenexin1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), 0.05% NaN3, 40% Glycerol
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:50-100 |
Product Details
Cenexin1 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to Cenexin1.
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Host Rabbit
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Clonality polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 95 kDa;Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 95 kDa
Fusion protein of human ODF2
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), 0.05% NaN3, 40% Glycerol
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Cenexin1 is a Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly
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Subcellular Localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Cell projection, cilium; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole; Cytoplasm, cytoskeleton, spindle pole; Cell projection, cilium, flagellum
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Expression
Tissue_Specificity: Testis-specific (at protein level). Highly expressed in cytoplasm of step 2 round spermatids. Detected in the middle piece and extends to about half the principal piece of the sperm tails. -
Isoforms & Post-Translational Modification
Cenexin1 has 10 isoforms, Q5BJF6-1: amino acid length is 829, molecular weight is 95401 Da (predicted); Q5BJF6-2: amino acid length is 763, molecular weight is 88578 Da (predicted); Q5BJF6-3: amino acid length is 805, molecular weight is 93254 Da (predicted); Q5BJF6-4: amino acid length is 824, molecular weight is 95348 Da (predicted); Q5BJF6-5: amino acid length is 638, molecular weight is 73339 Da (predicted); Q5BJF6-6: amino acid length is 657, molecular weight is 75433 Da (predicted); Q5BJF6-7: amino acid length is 701, molecular weight is 80886 Da (predicted); Q5BJF6-8: amino acid length is 638, molecular weight is 73666 Da (predicted); Q5BJF6-9: amino acid length is 576, molecular weight is 66967 Da (predicted); Q5BJF6-10: amino acid length is 657, molecular weight is 75691 Da (predicted).Tyrosine phosphorylated. Phosphorylated by TSSK4 on Ser-95
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Subunit
Self-associates.
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SwissProt ID
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Synonyms
CT134, ODF84, ODF2/1, ODF2/2
Documentation