CEP72 Antibody (YA8815)
(Synonyms: FLJ10565; KIAA1519; MGC5307)CEP72 Antibody (YA8815) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CEP72.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:500-800 |
Product Details
CEP72 Antibody (YA8815) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CEP72.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 71.5 kDa
Full length human recombiant protein of human CEP72 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CEP72 is involved in the recruitment of key centrosomal proteins to the centrosome. Provides centrosomal microtubule-nucleation activity on the gamma-tubulin ring complexes (gamma-TuRCs) and has critical roles in forming a focused bipolar spindle, which is needed for proper tension generation between sister chromatids. Required for localization of KIZ, AKAP9 and gamma-tubulin ring complexes (gamma-TuRCs). Involved in centriole duplication. Required for CDK5RAP22, CEP152, WDR62 and CEP63 centrosomal localization and promotes the centrosomal localization of CDK2[1][2].
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Subcellular Localization
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome,Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite
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Isoforms & Post-Translational Modification
Q9P209 has two isomers: Q9P209-1: 71718 Da (predicted); Q9P209-2: 21336 Da (predicted).
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Subunit
Interacts with KIZ, PCM1 and CDK5RAP2
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SwissProt ID
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Synonyms
FLJ10565; KIAA1519; MGC5307
Documentation
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