CGRP Antibody (YA6504)

Cat. No.: HY-P86811: Data Sheet COA
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CGRP Antibody (YA6504) is a Rat -derived and non-conjugated monoclonal antibody, targeting to CGRP.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CGRP Antibody (YA6504) is a Rat -derived and non-conjugated monoclonal antibody, targeting to CGRP.

Host

Rat

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 14 kDa;

Observed band size: 10 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P06881

Gene ID

796 [NCBI]

Immunogen

Recombinant protein within rat CGRP aa 1-128.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-F IHC-F: Immunohistochemistry-Frozen	1:500
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:2000
WB WB: Western Blot	1:2000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol, 0.2% Proclean 950.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：CGRP1/CALCA is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex (PubMed:1318039, PubMed:33602864, PubMed:9620797). Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role (PubMed:3492492). It also elevates platelet cAMP (PubMed:1318039). CGRP1 can also bind and activate CALCR-RAMP1 (AMYR1) receptor complex (PubMed:38603770)

Subcellular Localization：Secreted

Expression：
Tissue_Specificity: Expressed in spinal cord

Isoforms & Post-Translational Modification：P06881 has three isomers: P06881-1: 13899 Da (predicted); P01258-1: 15467 Da (predicted); P01258-2: 15535 Da (predicted).

Synonyms

Calcitonin/calcitonin related polypeptide alpha antibody; Alpha type CGRP antibody; Beta type CGRP antibody; CALC1 antibody; CALC2 antibody; CALCA antibody; CALCB antibody; Calcitonin 1 antibody; Calcitonin 2 antibody; Calcitonin gene related peptide I antibody; Calcitonin/calcitonin related polypeptide alpha antibody; Alpha type CGRP antibody; Beta type CGRP antibody; CALC1 antibody; CALC2 antibody; CALCA antibody; CALCB antibody; Calcitonin 1 antibody; Calcitonin 2 antibody; Calcitonin gene related peptide I antibody; Calcitonin gene related peptide II antibody; Calcitonin related polypeptide alpha antibody; Calcitonin related polypeptide beta antibody; CGRP antibody; CGRP I antibody; CGRP II antibody; CGRP1 antibody; CGRP2 antibody; CT antibody; Katacalcin antibody; KC antibody;

Documentation

Select Batch:

Data Sheet (231 KB) SDS (254 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)