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  4. Monoclonal Antibodies
  5. CHIA Antibody (YA8145)(PBS only)

CHIA Antibody (YA8145)(PBS only)

Cat. No.: HY-P88461A
User Guide for Antibodies Technical Support

CHIA Antibody (YA8145) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CHIA.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

CHIA Antibody (YA8145) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CHIA.
Host

Mouse
Species Reactivity
Human
SwissProt ID
Immunogen

Full length human Recombinant protein of human CHIA produced in E.coli.
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:2000-2500
Purity Affinity purified Conjugation Non-conjugated
Isotype IgG2a  
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding
Subcellular Localization：Secreted,Cytoplasm,Cytoplasm
Expression：
Tissue_Specificity: Detected in lung epithelial cells from asthma patients (at protein level). Highly expressed in stomach. Detected at lower levels in lung
Induction: Up-regulated in lung epithelial cells from asthma patients
Isoforms & Post-Translational Modification：Q9BZP6 has three isomers: Q9BZP6-1: 52271 Da (predicted); Q9BZP6-2: 40139 Da (predicted); Q9BZP6-3: 33906 Da (predicted).
Subunit：Interacts with EGFR
Synonyms
AMCASE; CHIT2; TSA1902
Documentation
User Guide for Antibodies (1077 KB)

CHIA Antibody (YA8145)(PBS only) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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CHIA Antibody (YA8145)(PBS only)
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