CHIA Antibody (YA8145)
(Synonyms: AMCASE; CHIT2; TSA1902)CHIA Antibody (YA8145) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CHIA.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:2000-2500 |
Product Details
CHIA Antibody (YA8145) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CHIA.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
Full length human Recombinant protein of human CHIA produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CHIA is a Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding
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Subcellular Localization
Secreted,Cytoplasm,Cytoplasm
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Expression
Tissue_Specificity: Detected in lung epithelial cells from asthma patients (at protein level). Highly expressed in stomach. Detected at lower levels in lung
Induction: Up-regulated in lung epithelial cells from asthma patients -
Isoforms & Post-Translational Modification
Q9BZP6 has three isomers: Q9BZP6-1: 52271 Da (predicted); Q9BZP6-2: 40139 Da (predicted); Q9BZP6-3: 33906 Da (predicted).
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Subunit
Interacts with EGFR
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SwissProt ID
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Synonyms
AMCASE; CHIT2; TSA1902
Documentation
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