CIAPIN1 Antibody (YA7899)(PBS only)

Cat. No.: HY-P88215A: Data Sheet User Guide for Antibodies
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CIAPIN1 Antibody (YA7899) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CIAPIN1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CIAPIN1 Antibody (YA7899) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CIAPIN1.

Host

Mouse

Molecular Weight

Predicted band size: 33.4 kDa

Species Reactivity

Human

SwissProt ID

Q6FI81

Immunogen

Human recombinant protein fragment corresponding to amino acids 97-312 of human CIAPIN1 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1 (PubMed:23596212). NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit (By similarity). Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity)

Subcellular Localization：Cytoplasm,Nucleus,Mitochondrion intermembrane space

Expression：
Tissue_Specificity: Ubiquitously expressed. Highly expressed in heart, liver and pancreas

Isoforms & Post-Translational Modification：Q6FI81 has three isomers: Q6FI81-1: 33582 Da (predicted); Q6FI81-2: 11735 Da (predicted); Q6FI81-3: 32213 Da (predicted).

Subunit：Monomer

Synonyms

Anamorsin; DRE2; PRO0915

Documentation

User Guide for Antibodies (1077 KB)