CIAPIN1 Antibody (YA7899)
(Synonyms: Anamorsin; DRE2; PRO0915)CIAPIN1 Antibody (YA7899) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CIAPIN1.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-4000 | 1:150-500 |
Product Details
CIAPIN1 Antibody (YA7899) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CIAPIN1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 33.4 kDa
Human recombinant protein fragment corresponding to amino acids 97-312 of human CIAPIN1 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CIAPIN1 component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells[1].
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Subcellular Localization
Cytoplasm,Nucleus,Mitochondrion intermembrane space
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Expression
Tissue_Specificity: Ubiquitously expressed. Highly expressed in heart, liver and pancreas -
Isoforms & Post-Translational Modification
Q6FI81 has three isomers: Q6FI81-1: 33582 Da (predicted); Q6FI81-2: 11735 Da (predicted); Q6FI81-3: 32213 Da (predicted).
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Subunit
Monomer
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SwissProt ID
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Synonyms
Anamorsin; DRE2; PRO0915
Documentation
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