CITED1 Antibody (YA8272)

Cat. No.: HY-P88588: Ficha de datos User Guide for Antibodies
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CITED1 Antibody (YA8272) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CITED1.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn
Referencias

Descripciòn

CITED1 Antibody (YA8272) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CITED1.

Host

Mouse

Clonality

Monoclonal

Peso molecular

Predicted band size: 19.7 kDa

Species Reactivity

Human

SwissProt ID

Q99966

Immunogen

Full length human recombinant protein of human CITED1 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Sensitivity	Endogenous	Pureza	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Transcriptional coactivator of the p300/CBP-mediated transcription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner

Subcellular Localization：Nucleus,Cytoplasm

Expression：
Tissue_Specificity: Expressed only in melanocytes and testis
Induction: Up-regulated by GPR39 in neuronal cells

Isoforms & Post-Translational Modification：Q99966 has two isomers: Q99966-1: 19896 Da (predicted); Q99966-2: 22613 Da (predicted).
Phosphorylated

Subunit：Interacts (via C-terminus) with CREBBP

Synonyms

MSG1

Documentación

User Guide for Antibodies (1077 KB)

Referencias

[1]. /biology-dictionary/a549-cell.html [Content Brief]