CYBC1 Antibody (YA8631)
(Synonyms: FLJ00406; FLJ90469; MGC4368)CYBC1 Antibody (YA8631) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CYBC1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
ICC/IF
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|
| Dilution Ratio | 1:100-250 |
Product Details
CYBC1 Antibody (YA8631) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CYBC1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 20.6 kDa
Full length human recombinant protein of human C17orf62 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CYBC1 functions as a chaperone necessary for a stable expression of the CYBA and CYBB subunits of the cytochrome b-245 heterodimer. Controls the phagocyte respiratory burst and is essential for innate immunity[1].
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Subcellular Localization
Endoplasmic reticulum membrane
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Expression
Tissue_Specificity: Highly expressed in macrophages, neutrophils and monocytes
Induction: In macrophages, expression is induced after treatment with IFNG or a combination of IFNG and Salmonella Tiphimurium -
Isoforms & Post-Translational Modification
Q9BQA9 has two isomers: Q9BQA9-1: 20774 Da (predicted); Q9BQA9-2: 19436 Da (predicted).
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Subunit
Interacts with CYBB; CYBC1 may act as a chaperone stabilizing Cytochrome b-245 heterodimer
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SwissProt ID
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Synonyms
FLJ00406; FLJ90469; MGC4368
Documentation
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