ddx24 Antibody (YA6847)

製品番号: HY-P87154: データシート User Guide for Antibodies
FAQs
Technical Support

ddx24 Antibody (YA6847) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ddx24.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

ddx24 Antibody (YA6847) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ddx24.

Host

Mouse

Clonality

Recombinant,Monoclonal

分子量

Predicted band size: 94.5 kDa

Species Reactivity

Zebrafish

SwissProt ID

Q9GZR7

Gene ID

57062 [NCBI]

Immunogen

Recombinant protein within zebrafish ddx24 aa 562-819 / 832.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:1000
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:50

純度	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：ATP-dependent RNA helicase that plays a role in various aspects of RNA metabolism including pre-mRNA splicing and is thereby involved in different biological processes such as cell cycle regulation or innate immunity (PubMed:24204270, PubMed:24980433). Plays an inhibitory role in TP53 transcriptional activity and subsequently in TP53 controlled cell growth arrest and senescence by inhibiting its EP300 mediated acetylation (PubMed:25867071). Negatively regulates cytosolic RNA-mediated innate immune signaling at least in part by affecting RIPK1/IRF7 interactions. Alternatively, possesses antiviral activity by recognizing gammaherpesvirus transcripts in the context of lytic reactivation (PubMed:36298642). Plays an essential role in cell cycle regulation in vascular smooth muscle cells by interacting with and regulating FANCA (Fanconi anemia complementation group A) mRNA (By similarity)|(Microbial infection) Plays a positive role in HIV-1 infection by promoting Rev-dependent nuclear export of viral RNAs and their packaging into virus particles (PubMed:24204270)

Subcellular Localization：Cytoplasm,Nucleus

Expression：
Tissue_Specificity: Ubiquitous. Most abundant in heart and brain, but with lowest levels in thymus and small intestine
Induction: By type I interferons

Isoforms & Post-Translational Modification：Q9GZR7 has two isomers: Q9GZR7-1: 96332 Da (predicted); Q9GZR7-2: 90298 Da (predicted).
Ubiquitinated by MDM2 without targeting DDX24 for proteasomal degradation

Subunit：Interacts with FADD (PubMed:24204270)

Synonyms

DEAD (Asp-Glu-Ala-Asp) box helicase 24 antibody; ddx24 antibody;

ドキュメンテーション

User Guide for Antibodies (1077 KB)

ddx24 Antibody (YA6847) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

最近チェックした製品:

製品名

カスタマ需要量 *

お名前 *

タイトル

メールアドレス *

電話番号 *

デパートメント

組纖名 *

市区町村

都道府県

国或いは地域 *

必ず会社名を記載ください。個人への返信は行いません。

備考

製品名

Lot #

お名前 *

国或いは地域 *

メールアドレス *

備考

お名前
メール *

	Sorry, but the email address you supplied was invalid.

ddx24 Antibody (YA6847)

Product Detail

Background

説明

ddx24 Antibody (YA6847) 関連分類

最近チェックした製品:

Request for HNMR Report

Request for HNMR Report