DEK Antibody (YA1210)
(Synonyms: Dek; DEK oncogene; Protein DEK)DEK Antibody (YA1210) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DEK.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.131.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:100-1:200 |
Product Details
DEK Antibody (YA1210) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DEK.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 50 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 43 kDa
Recombinant protein of human DEK
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.131.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DEK is involved in chromatin organization
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Subcellular Localization
Nucleus
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Expression
Tissue_specificity:Ubiquitous. Expressed at relatively high levels -
Isoforms & Post-Translational Modification
P35659 has 2 isomers: P35659-1: 42674 Da (predicted); P35659-2: 38705 Da (predicted).
Phosphorylated by CK2. Phosphorylation fluctuates during the cell cycle with a moderate peak during G(1) phase, and weakens the binding of DEK to DNA -
Subunit
Found in a mRNA splicing-dependent exon junction complex (EJC) with DEK, RBM8A, RNPS1, SRRM1 and ALYREF/THOC4. Interacts with histones H2A, H2B, H3, H4, acetylated histone H4, non-phosphorylated DAXX and HDAC2. Component of the B-WICH complex, at least composed of SMARCA5/SNF2H, BAZ1B/WSTF, SF3B1, DEK, MYO1C, ERCC6, MYBBP1A and DDX21. Binds DNA
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SwissProt ID
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Synonyms
Dek; DEK oncogene; Protein DEK
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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