DIXDC1 Antibody (YA8115)
(Synonyms: CCD1)DIXDC1 Antibody (YA8115) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DIXDC1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF
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Reactivity :
Human, Monkey, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100-250 |
Product Details
DIXDC1 Antibody (YA8115) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DIXDC1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Monkey, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 53.8 kDa
Full length human recombinant protein of human DIXDC1 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DIXDC1 is a Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2
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Subcellular Localization
Cell junction, focal adhesion,Cytoplasm, cytoskeleton, stress fiber,Cytoplasm,Cytoplasm
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Expression
Tissue_Specificity: Ubiquitously expressed with higher expression in cardiac and skeletal muscles -
Isoforms & Post-Translational Modification
Q155Q3 has four isomers: Q155Q3-1: 77478 Da (predicted); Q155Q3-2: 53942 Da (predicted); Q155Q3-4: 24428 Da (predicted); Q155Q3-5: 24313 Da (predicted).
Phosphorylated on tyrosine and serine residues丨Polyubiquitinated, leading to its proteasomal degradation -
Subunit
Isoform 1 but not isoform 2 binds filamentous actin
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SwissProt ID
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Synonyms
CCD1
Documentation
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