DLST Antibody (YA7706)
DLST Antibody (YA7706) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DLST.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human
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Formulation:
Supplied in 10mM TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:500-1000 |
Product Details
DLST Antibody (YA7706) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DLST.
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Host Rabbit
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Clonality Recombinant
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 49 kDa;
KLH conjugated synthetic peptide derived from human DLST
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 10mM TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DLST is a Dihydrolipoamide succinyltransferase (E2) component of the 2-oxoglutarate dehydrogenase complex. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A[1][2].
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Subcellular Localization
Mitochondrion matrix,Nucleus
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Isoforms & Post-Translational Modification
P36957 has two isomers: P36957-1: 48755 Da (predicted); P36957-2: 39553 Da (predicted).
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Subunit
The 2-oxoglutarate dehydrogenase complex is composed of OGDH (2-oxoglutarate dehydrogenase; E1), DLST (dihydrolipoamide succinyltransferase; E2), DLD (dihydrolipoamide dehydrogenase; E3) and the assembly factor KGD4 (By similarity)
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SwissProt ID
Documentation
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