DLX5 Antibody (YA2342)

Cat. No.: HY-P82597: Fiche technique COA
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User Guide for Antibodies
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DLX5 Antibody (YA2342) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DLX5.

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Size	Stock	Quantité
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10 μL	En stock	Estimated Time of Arrival: December 31
50 μL	En stock	Estimated Time of Arrival: December 31
100 μL	En stock	Estimated Time of Arrival: December 31
250 μL	Obtenir un devis

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DLX5 Antibody (YA2342) Recommandations en vedette:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Verification Image
Background
Description
Références

Description

DLX5 Antibody (YA2342) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DLX5.

Host

Rabbit

Clonality

Recombinant, Monoclonal

Masse moléculaire

Predicted band size: 32 kDa;

Observed band size: 32 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P56178

Gene ID

1749 [NCBI]

Immunogen

A synthesized peptide derived from human Dlx5 aa181-212.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200
IP IP: Immunoprecipitation	1:50

Sensitivity	Endogenous	Pureté	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Verification Image

IHC-P

Immunohistochemical analysis of paraffin-embedded Mouse heart tissue using DLX5 Antibody (YA2342). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (HY-P82597, 1/100) in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.
Immunohistochemical analysis of paraffin-embedded Mouse heart tissue using DLX5 Antibody (YA2342). The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0) for 2 minutes. The tissues were blocked in QuickBlock for 20 minutes at room temperature, washed with ddH2O and PBS, and then probed with the primary antibody (HY-P82597, 1/100) in 4℃ overnight. The detection was performed using an HRP conjugated compact polymer system. DAB was used as the chromogen. Tissues were counterstained with hematoxylin and mounted with DPX.

Background

Function：Transcriptional factor involved in bone development. Acts as an immediate early BMP-responsive transcriptional activator essential for osteoblast differentiation. Stimulates ALPL promoter activity in a RUNX2-independent manner during osteoblast differentiation. Stimulates SP7 promoter activity during osteoblast differentiation. Promotes cell proliferation by up-regulating MYC promoter activity. Involved as a positive regulator of both chondrogenesis and chondrocyte hypertrophy in the endochondral skeleton. Binds to the homeodomain-response element of the ALPL and SP7 promoter. Binds to the MYC promoter. Requires the 5'-TAATTA-3' consensus sequence for DNA-binding

Subcellular Localization：Nucleus

Isoforms & Post-Translational Modification：P56178 has 2 isomers: P56178-1: 31540 Da (predicted); P56178-2: 20900 Da (predicted).
Phosphorylated. Phosphorylation of Ser-34 and Ser-217 by MAPK14 enhances its transcriptional activity. Phosphorylation by CaMK2 increases its protein stability (By similarity)

Subunit：Interacts with XRCC6 (Ku70)

RRID

AB_3104698

Database

Entrez Gene: 1749 Human ; 13395 Mouse ; 25431 Rat

SwissProt: P56178 Human ; P70396 Mouse ; P50575 Rat

OMIM: 220600 Human

Research Field

Neuroscience

Synonyms

Distal less homeo box 5; Dlx 5; Homeo box protein DLX 5

Documentation

Select Batch:

Fiche technique (234 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

Références

[1]. /biology-dictionary/hepg2-cell.html [Content Brief]

DLX5 Antibody (YA2342) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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DLX5 Antibody (YA2342)

DLX5 Antibody (YA2342) Recommandations en vedette:

Product Detail

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Background

Description

Références

DLX5 Antibody (YA2342) Related Classifications

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