DnaJC7 Antibody
(Synonyms: TPR2, TTC2, DNAJC7, DnaJ homolog subfamily C member 7, Tetratricopeptide repeat protein 2, TPR repeat protein 2)DnaJC7 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to DnaJC7.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS (pH 7.4) containing 40% glycerol, and 0.05% sodium azide.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:50-100 |
Product Details
DnaJC7 Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to DnaJC7.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse
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Calculated Molecular Weight Predicted band size: 56 kDa
Recombinant protein of human DNAJC7.
Endogenous
Affinity purified
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4) containing 40% glycerol, and 0.05% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DnaJC7 acts as a co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm (By similarity)
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Subcellular Localization
Cytoplasm; Nucleus; Cytoplasm, cytoskeleton
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Isoforms & Post-Translational Modification
DnaJC7 has 2 isoforms, Q99615-1: amino acid length is 494, molecular weight is 56441 Da (predicted); Q99615-2: amino acid length is 438, molecular weight is 50097 Da (predicted).DnaJC7 存在 2 个异构体，Q99615-1：氨基酸个数为 494 个，分子量为 56441 Da (预测)；Q99615-2：氨基酸个数为 438 个，分子量为 50097 Da (预测)。
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Subunit
Associates with complexes containing chaperones HSP70 and HSP90.
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SwissProt ID
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Synonyms
TPR2, TTC2, DNAJC7, DnaJ homolog subfamily C member 7, Tetratricopeptide repeat protein 2, TPR repeat protein 2
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