DPEP3 Antibody (YA1235)(PBS only)
(Synonyms: DPEP3; UNQ834/PRO1772; Dipeptidase 3)DPEP3 Antibody (YA1235) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DPEP3.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:100-1:200 |
Product Details
DPEP3 Antibody (YA1235) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to DPEP3.
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Host Rabbit
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Species ReactivityHuman
A synthesized peptide derived from human DPEP3
Affinity Purified
Non-conjugated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DPEP3 is a Lacks dipeptidase activity and is unable to hydrolyze cystinyl-bis-glycine, leukotriene D4 and the beta-lactam antibiotic imipenem. The absence of activity may be due to the inability of asparagine (instead of aspartate found in DPEP1/2) at position 359 to function as the acid/base catalyst and activate the nucleophilic water/hydroxide. A tyrosine (instead of histidine) at position 269 reduces affinity for the beta zinc and may cause substrate steric hindrance[1].
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Subcellular Localization
Membrane; Lipid-anchor, GPI-anchor
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Subunit
Homodimer; disulfide-linked (PubMed:32325220).
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SwissProt ID
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Synonyms
DPEP3; UNQ834/PRO1772; Dipeptidase 3
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Research Field
Cell Biology
Documentation
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