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  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. Dysferlin Antibody (YA3036)

Dysferlin Antibody (YA3036)

Cat. No.: HY-P83291
COA
SDS
User Guide for Antibodies Technical Support

Dysferlin Antibody (YA3036) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Dysferlin.

For research use only. We do not sell to patients.

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50 μL In-stock
100 μL In-stock
250 μL   Get quote  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

Dysferlin Antibody (YA3036) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Dysferlin.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Molecular Weight
Predicted band size: 237 kDa;
Observed band size: 280 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human Dysferlin aa100-200.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:1000-1:2000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:100-1:200
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:50-1:200
Sensitivity Endogenous Purity Affinity Chromatography
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in rabbit IgG in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity)
Subcellular Localization：Cell membrane, sarcolemma; Single-pass type II membrane protein; Cytoplasmic vesicle membrane; Single-pass type II membrane protein; Cell membrane
Expression：
Tissue_specificity:Expressed in skeletal muscle, myoblast, myotube and in the syncytiotrophoblast (STB) of the placenta (at protein level) . Ubiquitous. Highly expressed in skeletal muscle. Also found in heart, brain, spleen, intestine, placenta and at lower levels in liver, lung, kidney and pancreas
Isoforms & Post-Translational Modification：O75923 has 15 isomers: O75923-1: 237295 Da (predicted); O75923-2: 240649 Da (predicted); O75923-3: 235913 Da (predicted); O75923-4: 239297 Da (predicted); O75923-5: 239267 Da (predicted); O75923-6: 237916 Da (predicted); O75923-7: 241269 Da (predicted); O75923-8: 240735 Da (predicted); O75923-9: 236000 Da (predicted); O75923-10: 239383 Da (predicted); O75923-11: 239353 Da (predicted); O75923-12: 238002 Da (predicted); O75923-13: 241356 Da (predicted); O75923-14: 237381 Da (predicted); O75923-15: 222315 Da (predicted).
Subunit：Interacts with CACNA1S. Interacts with ANXA1; the interaction is Ca(2+)- and injury state-dependent. Interacts with ANXA2; the interaction is Ca(2+)- and injury state-dependent. Interacts with CACNA1S and PARVB.
Database

Entrez Gene: 8291 Human ; 26903 Mouse ;

SwissProt: O75923 Human ; Q9ESD7 Mouse ;

OMIM: 253601 Human

Research Field

Cell Biology
Synonyms
DYSF; Dysferlin; Fer-1-like protein 1
Documentation
SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

Dysferlin Antibody (YA3036) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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