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EGF Antibody (YA469)

(Synonyms: Pro-epidermal growth factor, EGF, Egf)
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EGF Antibody (YA469) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EGF.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P, IP

  • Reactivity :

    Human

  • Formulation:

    Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Conjugation:
    Non-conjugated
  • EGF Antibody (YA469) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
IP Info
IP: Immunoprecipitation
Dilution Ratio 1:500-1:1000 1:50-1:100 1:10-1:50

Product Details

Description

EGF Antibody (YA469) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EGF.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 160 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 134 kDa
Species Reactivity Database

Entrez Gene: 1950 Human

SwissProt: P01133 Human

Immunogen

Synthetic peptide corresponding to Human EGF.AA range:201-350.

Sensitivity

Endogenous

Purification

Protein A affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

RRID

AB_3102827

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in 1*TBS (pH7.4), 0.05% BSA and 40% Glycerol. Preservative: 0.05% Sodium Azide.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Epidermal growth factor (EGF) is the prototypic member of the EGF superfamily of peptide growth factors, which is compose of a single-chain polypeptide containing a total of 53 amino acid residues. EGF is synthesized as a precursor consisting of 1217 amin

  • Subcellular Localization

    Membrane; Single-pass type I membrane protein

  • Expression


    Tissue_specificity:It is expressed in the kidneys, salivary glands, brain, and prostate.

  • Isoforms & Post-Translational Modification

    P01133 has 3 isomers: P01133-1: 133994 Da (predicted); P01133-2: 129256 Da (predicted); P01133-3: 129746 Da (predicted).
    O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor)

  • Subunit

    Interacts with EGFR and promotes EGFR dimerization. Interacts with RHBDF2 (By similarity).

  • SwissProt ID

    P01133

  • Gene ID
    1950 [NCBI]
  • Synonyms

    Pro-epidermal growth factor, EGF, Egf

  • Research Field

    Signal Transduction

EGF Antibody (YA469) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • EGF Antibody (YA469) Product Image