EIF2C1 Antibody (YA7744)(PBS only)
(Synonyms: EIF2C; EIF2C1; GERP95)EIF2C1 Antibody (YA7744) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EIF2C1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
EIF2C1 Antibody (YA7744) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to EIF2C1.
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Host Mouse
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 97 kDa
Human recombinant protein fragment corresponding to amino acids 226-490 of human EIF2C1 produced in E.coli.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
EIF2C1 is required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs)
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Subcellular Localization
Cytoplasm, P-body
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Isoforms & Post-Translational Modification
Q9UL18: 857 amino acids, molecular weight 97214 Da.
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Subunit
Interacts with DDB1, DDX5, DDX6, DHX30, DHX36, DDX47, DICER1, AGO2, ELAVL1, HNRNPF, IGF2BP1, ILF3, IMP8, MATR3, MOV10, PABPC1, PRMT5, RBM4, SART3, TNRC6B, UPF1 and YBX1
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SwissProt ID
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Synonyms
EIF2C; EIF2C1; GERP95
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