EPS15R Antibody (YA2776)
(Synonyms: EPS15R)
Based on 1 Customer Validation
EPS15R Antibody (YA2776) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EPS15R.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-1:5000 | 1:50 |
Product Details
EPS15R Antibody (YA2776) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EPS15R.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 130 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 94 kDa
Entrez Gene: 58513 Human
SwissProt: Q9UBC2 Human
A synthetic peptide of human EPS15R
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
EPS15R is a Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2
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Subcellular Localization
Cell membrane; Peripheral membrane protein; Nucleus; Membrane, coated pit
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Isoforms & Post-Translational Modification
Q9UBC2 has 4 isomers: Q9UBC2-1: 94255 Da (predicted); Q9UBC2-2: 99606 Da (predicted); Q9UBC2-3: 83248 Da (predicted); Q9UBC2-4: 66479 Da (predicted).
Phosphorylated on tyrosine residues by EGFR -
Subunit
Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Interacts with FCHO2. Interacts (via EH domains) with DAB2.
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SwissProt ID
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Synonyms
EPS15R
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Research Field
Signal Transduction
Documentation
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