EPS15R Antibody (YA2776)

Cat. No.: HY-P83031: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

EPS15R Antibody (YA2776) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EPS15R.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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EPS15R Antibody (YA2776) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

EPS15R Antibody (YA2776) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to EPS15R.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 94 kDa;

Observed band size: 130 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q9UBC2

Gene ID

58513 [NCBI]

Immunogen

A synthetic peptide of human EPS15R

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:5000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2

Subcellular Localization：Cell membrane; Peripheral membrane protein; Nucleus; Membrane, coated pit

Isoforms & Post-Translational Modification：Q9UBC2 has 4 isomers: Q9UBC2-1: 94255 Da (predicted); Q9UBC2-2: 99606 Da (predicted); Q9UBC2-3: 83248 Da (predicted); Q9UBC2-4: 66479 Da (predicted).
Phosphorylated on tyrosine residues by EGFR

Subunit：Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Interacts with FCHO2. Interacts (via EH domains) with DAB2.

Database

Entrez Gene: 58513 Human

SwissProt: Q9UBC2 Human

Research Field

Signal Transduction

Synonyms

EPS15R

Documentation

Select Batch:

Data Sheet (231 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

EPS15R Antibody (YA2776) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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EPS15R Antibody (YA2776)

EPS15R Antibody (YA2776) Featured Recommendations:

Product Detail

Background

Documentation

EPS15R Antibody (YA2776) Related Classifications

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