Ezrin Antibody (YA767)(PBS only)

製品番号: HY-P80664A: データシート User Guide for Antibodies
FAQs
Technical Support

Ezrin Antibody (YA767) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Ezrin.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

Ezrin Antibody (YA767) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Ezrin.

Host

Mouse

分子量

Predicted band size: 69 kDa;

Observed band size: 81 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P15311

Gene ID

7430 [NCBI]

Immunogen

Synthetic peptide corresponding to Human Ezrin.The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

純度	affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis

Subcellular Localization：Apical cell membrane; Peripheral membrane protein; Cytoplasmic side; Cell projection; Cell projection, microvillus membrane; Peripheral membrane protein; Cytoplasmic side; Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side; Cytoplasm, cell cortex; Cytoplasm, cytoskeleton; Cell projection, microvillus

Expression：
Tissue_specificity:It is expressed in the cerebral cortex, basal ganglia, hippocampus, pituitary gland, and optic nerve. Expression is weaker in the brainstem and diencephalon. Expression is stronger in the frontal gray matter than in white matter (protein level) . It is a component of the microvilli of intestinal epithelial cells. It is preferentially expressed in astrocytes of the hippocampus, frontal cortex, thalamus, parahippocampal cortex, amygdala, insula, and corpus callosum. Expression was not detected in neurons in most of the tissues studied.

Subunit：Monomer. Homodimer (PubMed:27364155). Interacts with MCC, PLEKHG6, PODXL, SCYL3/PACE1, NHERF1 and TMEM8B (PubMed:12651155, PubMed:15498789, PubMed:17616675, PubMed:17881735, PubMed:19555689, PubMed:9314537).

Research Field

Cell Biology

Synonyms

EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81

ドキュメンテーション

User Guide for Antibodies (1077 KB)

Ezrin Antibody (YA767)(PBS only) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Ezrin Antibody (YA767)(PBS only)

Product Detail

Background

説明

Ezrin Antibody (YA767)(PBS only) 関連分類

最近チェックした製品:

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