FAF1 Antibody (YA7979)
(Synonyms: CGI-03; hFAF1; HFAF1s; UBXD12; UBXN3A)FAF1 Antibody (YA7979) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to FAF1.
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Host:
Mouse
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Isotype:
IgG2b
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
FAF1 Antibody (YA7979) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to FAF1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 73.8 kDa
Human recombinant protein fragment corresponding to amino acids 415-650 of human FAF1 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
FAF1 is an Ubiquitin-binding protein. Required for the progression of DNA replication forks by targeting DNA replication licensing factor CDT1 for degradation. Potentiates but cannot initiate FAS-induced apoptosis[1][2].
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes -
Isoforms & Post-Translational Modification
Q9UNN5 has two isomers: Q9UNN5-1: 73954 Da (predicted); Q9UNN5-2: 56934 Da (predicted).
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Subunit
Interacts with CDT1 and ATPase VCP/p97 (PubMed:26842564)
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SwissProt ID
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Synonyms
CGI-03; hFAF1; HFAF1s; UBXD12; UBXN3A
Documentation
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