FBXO25 Antibody (YA8795)
(Synonyms: FBX25)FBXO25 Antibody (YA8795) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FBXO25.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:500-800 |
Product Details
FBXO25 Antibody (YA8795) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FBXO25.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 43.1 kDa
Human recombinant protein fragment corresponding to amino acids 1-191 of human FBXO25 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
FBXO25 is a Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. May play a role in accumulation of expanded polyglutamine (polyQ) protein huntingtin (HTT)
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Expressed in all brain tissue observed -
Isoforms & Post-Translational Modification
Q8TCJ0 has three isomers: Q8TCJ0-1: 43313 Da (predicted); Q8TCJ0-2: 42211 Da (predicted); Q8TCJ0-3: 34067 Da (predicted).
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Subunit
Part of a SCF (SKP1-cullin-F-box) protein ligase complex consisting of FBXO25, SKP1, CUL1 and RBX1
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SwissProt ID
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Synonyms
FBX25
Documentation
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