FGF13 Antibody (YA8070)
(Synonyms: FGF-13; FGF2; FHF-2; FHF2)FGF13 Antibody (YA8070) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FGF13.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:150-500 |
Product Details
FGF13 Antibody (YA8070) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FGF13.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 27.4 kDa
Full length human recombinant protein of human FGF13 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
FGF13 is a Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling. Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons[1][2][3].
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Subcellular Localization
Nucleus,Cytoplasm,Nucleus,Cytoplasm,Nucleus,Cytoplasm,Nucleus,Cytoplasm,Nucleus,Cell projection, filopodium,Cell projection, growth cone,Cell projection, dendrite,Cell membrane, sarcolemma,Cytoplasm
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Expression
Tissue_Specificity: Ubiquitously expressed. Predominantly expressed in the nervous system -
Isoforms & Post-Translational Modification
Q92913 has 5 isomers: Q92913-1: 27564 Da (predicted); Q92913-2: 21581 Da (predicted); Q92913-3: 28752 Da (predicted); Q92913-4: 22275 Da (predicted); Q92913-5: 25607 Da (predicted).
May be phosphorylated -
Subunit
Interacts with SCN8A; regulates SCN8A activity (PubMed:15282281, PubMed:21566136, PubMed:33245860)
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SwissProt ID
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Synonyms
FGF-13; FGF2; FHF-2; FHF2
Documentation
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