FGF13 Antibody (YA8070)

製品番号: HY-P88386: データシート User Guide for Antibodies
FAQs
Technical Support

FGF13 Antibody (YA8070) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FGF13.

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

FGF13 Antibody (YA8070) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to FGF13.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 27.4 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q92913

Immunogen

Full length human recombinant protein of human FGF13 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Sensitivity	Endogenous	純度	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity). Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching (By similarity). Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus (By similarity). Regulates voltage-gated sodium channel transport and function (PubMed:15282281, PubMed:33245860, PubMed:36696443). May also play a role in MAPK signaling (By similarity). Required for the development of axonal initial segment-targeting inhibitory GABAergic synapses made by chandelier neurons (By similarity)

Subcellular Localization：Nucleus,Cytoplasm,Nucleus,Cytoplasm,Nucleus,Cytoplasm,Nucleus,Cytoplasm,Nucleus,Cell projection, filopodium,Cell projection, growth cone,Cell projection, dendrite,Cell membrane, sarcolemma,Cytoplasm

Expression：
Tissue_Specificity: Ubiquitously expressed. Predominantly expressed in the nervous system

Isoforms & Post-Translational Modification：Q92913 has 5 isomers: Q92913-1: 27564 Da (predicted); Q92913-2: 21581 Da (predicted); Q92913-3: 28752 Da (predicted); Q92913-4: 22275 Da (predicted); Q92913-5: 25607 Da (predicted).
May be phosphorylated

Subunit：Interacts with SCN8A; regulates SCN8A activity (PubMed:15282281, PubMed:21566136, PubMed:33245860)

Synonyms

FGF-13; FGF2; FHF-2; FHF2

ドキュメンテーション

User Guide for Antibodies (1077 KB)

FGF13 Antibody (YA8070) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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FGF13 Antibody (YA8070)

Product Detail

Background

説明

FGF13 Antibody (YA8070) 関連分類

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