FOXL2 Antibody (YA1324)

製品番号: HY-P81579: データシート User Guide for Antibodies
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FOXL2 Antibody (YA1324) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FOXL2.

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

FOXL2 Antibody (YA1324) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to FOXL2.

Host

Rabbit

Clonality

Recombinant, Monoclonal

分子量

Predicted band size: 39 kDa;

Observed band size: 45 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse

SwissProt ID

O88470

Gene ID

668 [NCBI]

Immunogen

Peptide

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:100

Sensitivity	Endogenous	純度	Protein A
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, Glycerol and BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Transcriptional regulator. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Has apoptotic activity in ovarian cells. Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2. Is a regulator of CYP19 expression. Is a transcriptional repressor of STAR. Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element

Subcellular Localization：Nucleus

Expression：
Tissue_specificity:Expressed in the mesenchyme of developing eyelids. Expressed in ovaries throughout development and adulthood, localized to the undifferentiated granulosa cells in small and medium follicles as well as cumulus cells of preovulatory follicles. Expressed in the pituitary

Subunit：Interacts with ESR1. Interacts with UBE2I/UBC9 (By similarity). Interacts with SMAD3.

Database

Entrez Gene: 668 Human ; 26927 Mouse ;

SwissProt: P58012 Human ; O88470 Mouse ;

OMIM: 110100 Human

Research Field

Cell biology

Synonyms

PFRK

ドキュメンテーション

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/caov-3-cell-line-cell.html [Content Brief]