GLRX3 Antibody (YA8102)

Cat. No.: HY-P88418: Ficha de datos User Guide for Antibodies
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GLRX3 Antibody (YA8102) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GLRX3.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

GLRX3 Antibody (YA8102) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GLRX3.

Host

Mouse

Clonality

Monoclonal

Peso molecular

Predicted band size: 37.3 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

O76003

Immunogen

Full length human recombinant protein of human GLRX3 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000

Sensitivity	Endogenous	Pureza	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins (PubMed:26613676, PubMed:27519415). Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). Required for hemoglobin maturation (PubMed:23615448). Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity

Subcellular Localization：Cytoplasm, cytosol,Cytoplasm, cell cortex,Cytoplasm, myofibril, sarcomere, Z line

Expression：
Tissue_Specificity: Expressed in heart, spleen, testis and, to a lower extent, in thymus and peripheral blood leukocytes. Weakly expressed in lung, placenta, colon and small intestine

Isoforms & Post-Translational Modification：O76003: 335 amino acids, molecular weight 37432 Da.

Subunit：Homodimer; the homodimer is independent of 2Fe-2S clusters (PubMed:27519415)

Synonyms

GLRX4; GRX3; GRX4; PICOT; TXNL2; TXNL3

Documentación

User Guide for Antibodies (1077 KB)