GLRX3 Antibody (YA8102)
(Synonyms: GLRX4; GRX3; GRX4; PICOT; TXNL2; TXNL3)GLRX3 Antibody (YA8102) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GLRX3.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
WB
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500-2000 |
Product Details
GLRX3 Antibody (YA8102) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GLRX3.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 37.3 kDa
Full length human recombinant protein of human GLRX3 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
GLRX3 is a Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins. Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator. Required for hemoglobin maturation. Does not possess any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity[1][2][3].
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Subcellular Localization
Cytoplasm, cytosol,Cytoplasm, cell cortex,Cytoplasm, myofibril, sarcomere, Z line
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Expression
Tissue_Specificity: Expressed in heart, spleen, testis and, to a lower extent, in thymus and peripheral blood leukocytes. Weakly expressed in lung, placenta, colon and small intestine -
Isoforms & Post-Translational Modification
O76003: 335 amino acids, molecular weight 37432 Da.
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Subunit
Homodimer; the homodimer is independent of 2Fe-2S clusters (PubMed:27519415)
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SwissProt ID
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Synonyms
GLRX4; GRX3; GRX4; PICOT; TXNL2; TXNL3
Documentation
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