GNB2 Antibody (YA1613)(PBS only)

Cat. No.: HY-P81868A: Data Sheet User Guide for Antibodies
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GNB2 Antibody (YA1613) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GNB2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

GNB2 Antibody (YA1613) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GNB2.

Host

Rabbit

Molecular Weight

Predicted band size: 37 kDa;

Observed band size: 32 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P62879

Gene ID

2783 [NCBI]

Immunogen

A synthetic peptide of human GNB2

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IP IP: Immunoprecipitation	1:20

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction

Subcellular Localization：Cytoplasm, perinuclear region; Cell membrane

Expression：
Tissue_specificity:Expressed in all cardiac subcompartments and in the brain, with highest levels in the atrioventricular node and brain

Isoforms & Post-Translational Modification：P62879 has 2 isomers: P62879-1: 37331 Da (predicted); P62879-2: 25931 Da (predicted).

Subunit：G proteins are composed of 3 units, alpha, beta and gamma. In this context, interacts with GNAI2 and GNG2 (PubMed:28219978). Interacts with ARHGEF18 and RASD2. Interacts with ATXN10. Interacts with SCN8A (PubMed:26900580)

Research Field

Signal Transduction

Synonyms

Gnb2; Gnb2l1; RACK1; Transducin beta chain 2

Documentation

User Guide for Antibodies (1077 KB)