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GRAP2 Antibody (YA1078)

(Synonyms: P38; GADS; GRID; GRPL; GrbX; Mona; GRB2L; GRBLG; Grf40; GRAP-2)

GRAP2 Antibody (YA1078) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to GRAP2.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

  • Conjugation:
    Non-conjugated
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

GRAP2 Antibody (YA1078) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to GRAP2.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 38 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 38 kDa
Species Reactivity Database

Entrez Gene: 9402 Human

SwissProt: O75791 Human

Immunogen

Recombinant protein of human GRAP2.

Sensitivity

Endogenous

Purification

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    GRAP2 interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc

  • Subcellular Localization

    Nucleus; Cytoplasm; Endosome

  • Isoforms & Post-Translational Modification

    O75791 has 2 isomers: O75791-1: 37909 Da (predicted); O75791-2: 24382 Da (predicted).

  • Subunit

    Interacts with phosphorylated LAT and LAX1 upon TCR activation. Interacts with SHB. Interacts with PTPN23

  • SwissProt ID

    O75791

  • Gene ID
    9402 [NCBI]
  • Synonyms

    P38; GADS; GRID; GRPL; GrbX; Mona; GRB2L; GRBLG; Grf40; GRAP-2

  • Research Field

    Signal Transduction

GRAP2 Antibody (YA1078) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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