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GRM4 Antibody (YA7804)

(Synonyms: GPRC1D; mGlu4; MGLUR4)

GRM4 Antibody (YA7804) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GRM4.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Conjugation:
    Non-conjugated
  • GRM4 Antibody (YA7804) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:500-800

Product Details

Description

GRM4 Antibody (YA7804) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GRM4.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 101.87 kDa
Immunogen

Human recombinant protein fragment corresponding to amino acids 126-407 of human GRM4 produced in E.coli.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG2a

Product Properties

  • Appearance

    Liquid

  • Formulation

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    GRM4 is a G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity

  • Subcellular Localization

    Cell membrane

  • Expression


    Tissue_Specificity: Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver

  • Isoforms & Post-Translational Modification

    Q14833 has 5 isomers: Q14833-1: 101868 Da (predicted); Q14833-2: 86683 Da (predicted); Q14833-3: 83580 Da (predicted); Q14833-4: 87353 Da (predicted); Q14833-5: 88493 Da (predicted).

  • Subunit

    Interacts with PICK1

  • SwissProt ID

    Q14833

  • Synonyms

    GPRC1D; mGlu4; MGLUR4

GRM4 Antibody (YA7804) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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