1. Antibodies
  2. Primary Antibodies
  3. Monoclonal Antibodies
  4. GTF2H3 Antibody (YA8848)

GTF2H3 Antibody (YA8848)

製品番号: HY-P89164
User Guide for Antibodies Technical Support

GTF2H3 Antibody (YA8848) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GTF2H3.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量 在庫状況
50 μL   お問い合わせ  
100 μL   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay
  • Product Detail

  • Background

  • 説明

製品説明

GTF2H3 Antibody (YA8848) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GTF2H3.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 34.2 kDa

Species Reactivity
Human, Mouse, Rat
SwissProt ID
Immunogen

Human recombinant protein fragment corresponding to amino acids 1-241 of human GTF2H3 produced in E.coli.

Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-2000
Sensitivity Endogenous 純度 Affinity purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG1  
Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background
Function:Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription
Subcellular Localization:Nucleus
Isoforms & Post-Translational Modification:Q13889 has two isomers: Q13889-1: 34378 Da (predicted); Q13889-2: 29777 Da (predicted).
Subunit:Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:27193682)
Synonyms
BTF2; P34; TFB4; TFIIH
ドキュメンテーション

GTF2H3 Antibody (YA8848) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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備考

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Inquiry Information

製品名:
GTF2H3 Antibody (YA8848)
製品番号:
HY-P89164
数量:
MCE 日本正規代理店: