GTF3C4 Antibody (YA8843)

Cat. No.: HY-P89159: Ficha de datos User Guide for Antibodies
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GTF3C4 Antibody (YA8843) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GTF3C4.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

GTF3C4 Antibody (YA8843) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GTF3C4.

Host

Mouse

Clonality

Monoclonal

Species Reactivity

Human, Monkey, Mouse, Rat

SwissProt ID

Q9UKN8

Immunogen

Human recombinant protein fragment corresponding to amino acids 583-822 of human GTF3C4 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:500-800

Sensitivity	Endogenous	Pureza	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin (PubMed:10523658). Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3 (PubMed:10523658). May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F (PubMed:10523658). May be localized close to the A box (PubMed:10523658)

Subcellular Localization：Nucleus

Isoforms & Post-Translational Modification：Q9UKN8: 822 amino acids, molecular weight 91982 Da.

Subunit：Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6

Synonyms

KAT12; TF3C-delta; TFIII90; TFIIIC90; TFIIIC290; TFIIICDELTA

Documentación

User Guide for Antibodies (1077 KB)