GTF3C4 Antibody (YA8843)
(Synonyms: KAT12; TF3C-delta; TFIII90; TFIIIC90; TFIIIC290; TFIIICDELTA)GTF3C4 Antibody (YA8843) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GTF3C4.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Monkey, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:500-800 |
Product Details
GTF3C4 Antibody (YA8843) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GTF3C4.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Monkey, Mouse, Rat
Human recombinant protein fragment corresponding to amino acids 583-822 of human GTF3C4 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
GTF3C4 is essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box[1].
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
Q9UKN8: 822 amino acids, molecular weight 91982 Da.
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Subunit
Part of the TFIIIC subcomplex TFIIIC2, consisting of six subunits, GTF3C1, GTF3C2, GTF3C3, GTF3C4, GTF3C5 and GTF3C6
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SwissProt ID
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Synonyms
KAT12; TF3C-delta; TFIII90; TFIIIC90; TFIIIC290; TFIIICDELTA
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