H2AFY2 Antibody (YA7908)
(Synonyms: MACROH2A2, macroH2A2, Core histone macro-H2A.2,H2AFY2)H2AFY2 Antibody (YA7908) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to H2AFY2.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:150-500 |
Product Details
H2AFY2 Antibody (YA7908) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to H2AFY2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
Human recombinant protein fragment corresponding to amino acids 2-261 of human H2AFY2 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Shipping
Shipping with blue ice.
Background
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Function
H2AFY2 is a Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation
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Subcellular Localization
Nucleus,Chromosome
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Isoforms & Post-Translational Modification
Q9P0M6: 372 amino acids, molecular weight 40058 Da.
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Subunit
The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers
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SwissProt ID
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Synonyms
MACROH2A2, macroH2A2, Core histone macro-H2A.2,H2AFY2
Documentation
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