HBEGF Antibody (YA4641)(PBS only)

Cat. No.: HY-P84945A: Fiche technique User Guide for Antibodies
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HBEGF Antibody (YA4641) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HBEGF.

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Size		Stock
50 μL		Obtenir un devis
100 μL		Obtenir un devis

* Veuillez sélectionner la quantité avant d'ajouter des articles.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description

Description

HBEGF Antibody (YA4641) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HBEGF.

Host

Rabbit

Masse moléculaire

Predicted band size: 23 kDa;

Observed band size: 23 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q99075

Gene ID

1839 [NCBI]

Immunogen

A synthetic peptide of human HBEGF

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Pureté	Affinity Chromatography	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor

Subcellular Localization：Secreted, extracellular space; Cell membrane; Single-pass type I membrane protein

Subunit：Interacts with FBLN1 (By similarity). Interacts with EGFR and ERBB4

Synonyms

DTR; DTS; DTSF; HB-EGF; HBEGF; HEGFL

Documentation

User Guide for Antibodies (1077 KB)