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Cat. No.: HY-P85199

HFE Antibody (YA4891)

Name: HFE Antibody (YA4891)
Brand: MedChemExpress
SKU: HY-P85199
Availability: PreOrder

(Synonyms: HFE; HLAH; Hereditary hemochromatosis protein; HLA-H)

HFE Antibody (YA4891) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to HFE.

For research use only. We do not sell to patients.

Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	ICC/IF ICC/IF: Immunocytochemistry/ Immunofluorescence	ELISA ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio	1:500-1:2000	1:200-1:1000	1:10000

Description

HFE Antibody (YA4891) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to HFE.

Immunogen

Purified recombinant fragment of human HFE expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

HFE binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin
Subcellular Localization

Cell membrane; Single-pass type I membrane protein
Expression

Tissue_specificity:Expressed in all tissues tested except brain
Isoforms & Post-Translational Modification

Q30201 has 11 isomers: Q30201-1: 40108 Da (predicted); Q30201-2: 29633 Da (predicted); Q30201-3: 38625 Da (predicted); Q30201-4: 28151 Da (predicted); Q30201-5: 37514 Da (predicted); Q30201-6: 18734 Da (predicted); Q30201-7: 29194 Da (predicted); Q30201-8: 32243 Da (predicted); Q30201-9: 18651 Da (predicted); Q30201-10: 27711 Da (predicted); Q30201-11: 8208 Da (predicted).
Subunit

Binds TFR through the extracellular domain in a pH-dependent manner
SwissProt ID

Q30201
Gene ID

3077 [NCBI]
Synonyms

HFE; HLAH; Hereditary hemochromatosis protein; HLA-H