HIST1H2BA Antibody (YA8138)

製品番号: HY-P88454: データシート User Guide for Antibodies
FAQs
Technical Support

HIST1H2BA Antibody (YA8138) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HIST1H2BA.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

HIST1H2BA Antibody (YA8138) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HIST1H2BA.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 14 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q96A08

Immunogen

Human recombinant protein fragment corresponding to amino acids 2-127 of human HIST1H2BA produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Sensitivity	Endogenous	純度	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Variant histone specifically required to direct the transformation of dissociating nucleosomes to protamine in male germ cells (By similarity). Entirely replaces classical histone H2B prior nucleosome to protamine transition and probably acts as a nucleosome dissociating factor that creates a more dynamic chromatin, facilitating the large-scale exchange of histones (By similarity). Core component of nucleosome (By similarity). Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template (By similarity). Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability (By similarity). DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). Also found in fat cells, its function and the presence of post-translational modifications specific to such cells are still unclear (PubMed:21249133)

Subcellular Localization：Nucleus,Chromosome

Expression：
Tissue_Specificity: Mainly expressed in testis, and the corresponding protein is also present in mature sperm (at protein level). Also found in some fat cells

Isoforms & Post-Translational Modification：Q96A08: 127 amino acids, molecular weight 14167 Da.

Subunit：The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers

Synonyms

bA317E16.3; H2BFU; STBP; TH2B; TSH2B; TSH2B.1

ドキュメンテーション

User Guide for Antibodies (1077 KB)

HIST1H2BA Antibody (YA8138) 関連分類

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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HIST1H2BA Antibody (YA8138)

Product Detail

Background

説明

HIST1H2BA Antibody (YA8138) 関連分類

最近チェックした製品:

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