2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. HMGA2 Antibody (YA1186)

HMGA2 Antibody (YA1186) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HMGA2.

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Tamaño Precio Stock Cantidad
20 μL Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Obtener un presupuesto 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Obtener un presupuesto  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Descripciòn

Descripciòn

HMGA2 Antibody (YA1186) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HMGA2.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Peso molecular
Predicted band size: 12 kDa;
Observed band size: 18 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

Recombinant protein of human HMGA2
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:500-1:1000
Sensitivity Endogenous Pureza Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Envío

Shipping with blue ice.
Background
Function：Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity). Positively regulates IGF2 expression through PLAG1 and in a PLAG1-independent manner (PubMed:28796236)
Subcellular Localization：Nucleus
Isoforms & Post-Translational Modification：P52926 has 6 isomers: P52926-1: 11832 Da (predicted); P52926-2: 11456 Da (predicted); P52926-3: 9273 Da (predicted); P52926-4: 10063 Da (predicted); P52926-5: 10845 Da (predicted); P52926-6: 9742 Da (predicted).
Regulated by cell cycle-dependent phosphorylation which alters its DNA binding affinity. Phosphorylated by NEK2 (By similarity)
Subunit：Interacts with E4F1 (PubMed:14645522).
Database

Entrez Gene: 8091 Human

SwissProt: P52926 Human

OMIM: 618908 Human

Research Field

Neuroscience
Synonyms
HMGA2; HMGIC; High mobility group protein HMGI-C; High mobility group AT-hook protein 2
Documentación
User Guide for Antibodies (1077 KB)

HMGA2 Antibody (YA1186) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
HMGA2 Antibody (YA1186)
Cat. No.:
HY-P81441
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MCE Japan Authorized Agent:

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