HOXA9 Antibody (YA9687)
(Synonyms: ABD-B, Abd-B, drosophila, homolog of, D6a9, Homeobox 1G, Homeobox A9, Homeobox protein Hox-1.7, Homeobox protein Hox-1G, Homeobox protein Hox-A9, Homeodomain protein HOXA9, Hox-1.7)HOXA9 Antibody (YA9687) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to HOXA9.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human
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Formulation:
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000 | 1:200 |
Product Details
HOXA9 Antibody (YA9687) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to HOXA9.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 30 kDa;
Synthetic peptide of human HOXA9 (aa 223-272).
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
HOXA9 is a Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Required for induction of SELE/E-selectin and VCAM1 on the endothelial cells surface at sites of inflammation. Positively regulates EIF4E-mediated mRNA nuclear export and also increases the translation efficiency of ODC mRNA in the cytoplasm by competing with factors which repress EIF4E activity such as PRH (By similarity)[1].
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Subcellular Localization
Nucleus; Cytoplasm
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Isoforms & Post-Translational Modification
HOXA9 has an amino acid length of 272, molecular weight is 30172 Da.
Methylated on Arg-140 by PRMT5; methylation is critical for E-selectin induction -
Subunit
Transiently interacts with PRMT5 in TNF stimulated endothelial cells.
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SwissProt ID
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Synonyms
ABD-B, Abd-B, drosophila, homolog of, D6a9, Homeobox 1G, Homeobox A9, Homeobox protein Hox-1.7, Homeobox protein Hox-1G, Homeobox protein Hox-A9, Homeodomain protein HOXA9, Hox-1.7
Documentation
References
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