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HR Antibody (YA8255)(PBS only)

(Synonyms: ALUNC; AU; HSA277165; HYPT4; MUHH; MUHH1)

HR Antibody (YA8255) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HR.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • HR Antibody (YA8255)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:100-500

Product Details

Description

HR Antibody (YA8255) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to HR.

  • Host Mouse
  • Species Reactivity
    Human
  • Calculated Molecular Weight Predicted band size: 127.3 kDa
Immunogen

Human recombinant protein fragment corresponding to amino acids 946-1189 of human HR produced in E.coli.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    HR is a Histone demethylase that specifically demethylates both mono- and dimethylated 'Lys-9' of histone H3. May act as a transcription regulator controlling hair biology (via targeting of collagens), neural activity, and cell cycle

  • Subcellular Localization

    Nucleus

  • Expression


    Tissue_Specificity: Strongest expression of isoforms 1 and 2 is seen in the small intestine, weaker expression in brain and colon, and trace expression is found in liver, pancreas, spleen, thymus, stomach, salivary gland, appendix and trachea. Isoform 1 is always the most abundant. Isoform 1 is exclusively expressed at low levels in kidney and testis. Isoform 2 is exclusively expressed at high levels in the skin

  • Isoforms & Post-Translational Modification

    O43593 has two isomers: O43593-1: 127495 Da (predicted); O43593-2: 121857 Da (predicted).

  • SwissProt ID

    O43593

  • Synonyms

    ALUNC; AU; HSA277165; HYPT4; MUHH; MUHH1

HR Antibody (YA8255)(PBS only) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • HR Antibody (YA8255)(PBS only) Product Image