HspB8 Antibody (YA5438)

Cat. No.: HY-P85746: Data Sheet User Guide for Antibodies
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HspB8 Antibody (YA5438) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to HspB8.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	Get quote 2 - 3 weeks 1 - 2 Weeks 3 - 4 weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

HspB8 Antibody (YA5438) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to HspB8.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Observed band size: 22 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Rat, Mouse

SwissProt ID

Q9UJY1

Gene ID

26353 [NCBI]

Immunogen

Recombinant Protein of HSPB8/HSP22

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-2000

Purity	affinity chromatography.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Involved in the chaperone-assisted selective autophagy (CASA), a crucial process for protein quality control, particularly in mechanical strained cells and tissues such as muscle. Displays temperature-dependent chaperone activity

Subcellular Localization：Cytoplasm; Nucleus

Expression：
Tissue_specificity:It is mainly expressed in skeletal muscle and heart.

Induction:By 17-beta-estradiol

Subunit：Monomer. Forms a ternary complex with BAG3 and HSPA1A (PubMed:27884606). Component of the chaperone-assisted selective autophagy (CASA) complex consisting of BAG3, HSPA8/HSC70, HSPB8 and STUB1/CHIP (PubMed:20060297). Interacts with HSPB1 (PubMed:11342557). Interacts with DNAJB6 (PubMed:22366786). Interacts with BAG3 (PubMed:28144995)

Synonyms

HSPB8; CRYAC; E2IG1; HSP22; PP1629; Heat shock protein beta-8; HspB8; Alpha-crystallin C chain; E2-induced gene 1 protein; Protein kinase H11; Small stress protein-like protein HSP22

Documentation

User Guide for Antibodies (1077 KB)