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IFN alpha 1 Antibody

(Synonyms: IFNA13, IFNA1, Interferon alpha-1/13, IFN-alpha-1/13, Interferon alpha-D, LeIF D)

IFN alpha 1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to IFN alpha 1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.

  • Conjugation:
    Non-conjugated
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:1000-2000 1:100-200

Product Details

Description

IFN alpha 1 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to IFN alpha 1.

  • Host Rabbit
  • Clonality Polyclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 19 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 21 kDa
Immunogen

Synthetic peptide corresponding to the center region of human IFN alpha 1.

Sensitivity

Endogenous

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    IFN alpha 1 belongs to the type I interferon family and is an important member of the body's first line of defense against viral infection. IFN alpha 1 binds to the interferon α receptor (IFNAR) on the cell surface. After binding, it activates intracellular signaling pathways (such as the JAK-STAT pathway), ultimately upregulating the expression of hundreds of interferon-stimulated genes. The proteins encoded by these genes work together to perform antiviral and antiproliferative functions. IFN alpha 1 is a protein with strong antiviral and immunomodulatory functions[1].

  • Subunit

    Interacts with CR2.

  • SwissProt ID

    P0DY56

  • Gene ID
    3439; 3447 [NCBI]
  • Synonyms

    IFNA13, IFNA1, Interferon alpha-1/13, IFN-alpha-1/13, Interferon alpha-D, LeIF D

References

[1]. Liu J, et al. IFNA1 and IFNA13 Genes Confer Genetic Predisposition to Ankylosing Spondylitis-Associated Uveitis in a Chinese Population. Curr Eye Res. 2021 Apr;46(4):585-591. [Content Brief]

IFN alpha 1 Antibody Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • IFN alpha 1 Antibody Product Image