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IFNGR2 Antibody (YA7895)

(Synonyms: AF-1; IFGR2; IFNGT1; IMD28)

IFNGR2 Antibody (YA7895) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to IFNGR2.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2b

  • Application:

    IHC-P

  • Reactivity :

    Human

  • Formulation:

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Conjugation:
    Non-conjugated
  • IFNGR2 Antibody (YA7895) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:150-500

Product Details

Description

IFNGR2 Antibody (YA7895) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to IFNGR2.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human
  • Calculated Molecular Weight Predicted band size: 35 kDa
Immunogen

Full length human recombinant protein of human IFNGR2 produced in HEK293T cell.

Sensitivity

Endogenous

Purification

Affinity purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG2b

Product Properties

  • Appearance

    Liquid

  • Formulation

    Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    IFNGR2 associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG). Ligand binding stimulates activation of the JAK/STAT signaling pathway. Required for signal transduction in contrast to other receptor subunit responsible for ligand binding[1][2][3][4].

  • Subcellular Localization

    Cell membrane,Cytoplasmic vesicle membrane,Golgi apparatus membrane,Endoplasmic reticulum membrane,Cytoplasm

  • Expression


    Tissue_Specificity: Expressed in T-cells (at protein level)

  • Isoforms & Post-Translational Modification

    P38484: 337 amino acids, molecular weight 37806 Da.

  • Subunit

    Heterodimer with IFNGR1, to form the IFNG receptor complex (PubMed:7615558)

  • SwissProt ID

    P38484

  • Synonyms

    AF-1; IFGR2; IFNGT1; IMD28

IFNGR2 Antibody (YA7895) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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