IFNGR2 Antibody (YA7895)

Cat. No.: HY-P88211: Data Sheet User Guide for Antibodies
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IFNGR2 Antibody (YA7895) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to IFNGR2.

For research use only. We do not sell to patients.

Size	Price	Stock
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

IFNGR2 Antibody (YA7895) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to IFNGR2.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 35 kDa

Species Reactivity

Human

SwissProt ID

P38484

Immunogen

Full length human recombinant protein of human IFNGR2 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500

Sensitivity	Endogenous	Purity	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2b

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:7673114, PubMed:8124716). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:15356148, PubMed:7673114, PubMed:8124716). Required for signal transduction in contrast to other receptor subunit responsible for ligand binding (PubMed:7673114)

Subcellular Localization：Cell membrane,Cytoplasmic vesicle membrane,Golgi apparatus membrane,Endoplasmic reticulum membrane,Cytoplasm

Expression：
Tissue_Specificity: Expressed in T-cells (at protein level)

Isoforms & Post-Translational Modification：P38484: 337 amino acids, molecular weight 37806 Da.

Subunit：Heterodimer with IFNGR1, to form the IFNG receptor complex (PubMed:7615558)

Synonyms

AF-1; IFGR2; IFNGT1; IMD28

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/mda-mb-435-cell.html [Content Brief]