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IFT88 Antibody (YA3069)

(Synonyms: Recessive polycystic kidney disease protein Tg737 homolog; Tetratricopeptide repeat protein 10; TPR repeat protein 10)

IFT88 Antibody (YA3069) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IFT88.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Conjugation:
    Non-conjugated
  • IFT88 Antibody (YA3069) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
Dilution Ratio 1:500-1:1000

Product Details

Description

IFT88 Antibody (YA3069) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IFT88.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human, Mouse, Rat
  • Observed Molecular Weight
    Observed band size: 93 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 93 kDa
Species Reactivity Database
Immunogen

A synthetic peptide of human IFT88

Sensitivity

Endogenous

Purification

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    IFT88 is a Positively regulates primary cilium biogenesis. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment[1].

  • Subcellular Localization

    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole; Cell projection, cilium; Cytoplasm, cytoskeleton, cilium basal body; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Cytoplasm; Cell projection, cilium, flagellum; Cytoplasm, cytoskeleton

  • Expression


    Tissue_specificity:It is expressed in the heart, brain, liver, lungs, kidneys, skeletal muscle, and pancreas.

  • Isoforms & Post-Translational Modification

    Q13099 has 3 isomers: Q13099-2: 93192 Da (predicted); Q13099-1: 94270 Da (predicted); Q13099-3: 92381 Da (predicted).

  • Subunit

    Component of the IFT complex B, at least composed of IFT20, IFT22, IFT25, IFT27, IFT46, IFT52, TRAF3IP1/IFT54, IFT57, IFT74, IFT80, IFT81, and IFT88 (By similarity)

  • SwissProt ID

    Q13099

  • Gene ID
    8100 [NCBI]
  • Synonyms

    Recessive polycystic kidney disease protein Tg737 homolog; Tetratricopeptide repeat protein 10; TPR repeat protein 10

  • Research Field

    Epigenetics and Nuclear Signaling

[1]. Pugacheva EN, et al. HEF1-dependent Aurora A activation induces disassembly of the primary cilium. Cell. 2007 Jun 29;129(7):1351-63. [Content Brief]

IFT88 Antibody (YA3069) Related Classifications

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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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